Ofloxacin is the active constituent present in Ocuflox Eye Drops. It is 0.3% sterile ophthalmic solution. It is prescribed for treating conjunctivitis and corneal ulcers. This medication can be used only for treating bacterial eye infections. It cannot treat any other types of eye infection. The active constituent belongs to a class of drugs called ‘Quinolones’. It acts by interfering with bacterial DNA.
The active constituent, Ofloxacin is a synthetic fluoroquinolone and is used for treating pneumonia, bronchitis, urinary tract infections, gonococcal infections, and certain types of infectious diarrhea. This drug molecule was patented in 1980 and was approved for therapeutic use in 1985. The molecule weight of Ofloxacin is C18H20FN3O4 and the molecular weight is 361.37g/mol. Ocuflox Eye Drops medication is included in the World Health Organization’s List of Essential Medicines, which lists effective and safe medicines required in a health system.
The active component present in Ocuflox Eye drops is a broad-spectrum antibiotic. It is effective against both gram-positive and gram-negative bacteria. It has bactericidal action. Ocuflox Eye Drops inhibits bacterial DNA replication by attaching itself to an enzyme called DNA gyrase. It also inhibits topoisomerase IV, which is required to separate a replicated DNA, thereby stopping bacterial cell division. Ofloxacin has 100 times more affinity for bacterial DNA gyrase than mammalian.
Ocuflox Eye Drops can produce a stinging or burning sensation in the eyes for a minute or two after using it. The other most commonly observed side effects of Ocuflox Eye Drops include-
The above side effects are mild and temporary. Call your doctor right away if any of the above side effects aggravate or last for a long duration. Serious side effects eye pain, swelling of your eyelids or face are generally not observed with this medication. However, seek immediate medical help if they are observed.
Ocuflox eye drops are used for treating bacterial eye infections. They are mainly prescribed for treating conjunctivitis and corneal ulcers. It is available on prescription. It contains Ofloxacin as the active constituent, which belongs to a class of quinolone antibiotics. Remember, this drug product does not treat any other types of eye infections.
Ocuflox Eye Drops generally do not produce nausea. The most commonly observed side effects of this drug product include temporary blurred vision, itching, redness in eyes, and sensitivity to light. These side effects are mild and they do not last for a long time. However, call your doctor right away if any of these side effects exacerbate or continue for a longer time.
For treating conjunctivitis in adults and children of one year of age and above, one drop must be instilled in the affected eye every two to four hours for two days followed by one drop in each eye four times a day for about five days. Ocuflox Eye Drops are not for use in anyone below one-year-old.
Ofloxacin, the active constituent present in this drug product has more affinity towards bacterial DNA gyrase than mammalian. It inhibits the enzymes DNA gyrase and topoisomerase IV, which are required for DNA replication and separation of replicated DNA, resulting in inhibition of cell division.
Wash your hands before using this drug product. Instill drops in each of the eyes by tilting your head back and holding the dropper directly over each eye. Avoid touching the tip of the dropper to eyes or any other surface to prevent contamination. Use Ocuflox Eye Drops only after consulting a physician. Never use this medication in smaller or larger amounts or more often than advised by your physician.
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