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Modafinil is an active constituent present in Provigil. It is believed to act by altering natural substances such as neurotransmitters in the brain. Provigil is prescribed for treating excessive sleepiness produced by narcolepsy, sleep apnea, and shift work disorder. This formulation is not meant for curing sleep disorders and may not help you to get rid of all sleepiness. This medication is to be taken by mouth. This medication is available only on prescription and is not recommended for use in persons below 17 years of age. A generic version of Provigil Generic is also available in the market.

The active constituent, Modafinil belongs to a class of drugs called wakefulness-promoting agents. Modafinil was approved for therapeutic use in the United States in 1998. The molecular formula of this drug is C15H15NO2S and its molecular weight is 273.35. This drug molecule is practically insoluble in water. Provigil medication is also used in the treatment of hypersomnia, a disorder in which persons lack meaningful sleep and may need ten or more hours of sleep every day. Current studies have discovered that this drug may fight cocaine addiction. This drug is less likely to develop addiction and dependence. In the US, it is classified as a schedule IV controlled substance.

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  • The action of this medicine starts within 20 to 60 minutes.
  • The effect of this medicine lasts for about five to ten hours post oral administration.
  • The FDA has approved Provigil in December 1998.
  • It helps treat excessive sleepiness associated with narcolepsy, shift work disorder or obstructive sleep apnea (OSA).

The exact mechanism by which this medication produces an effect is unknown in spite of numerous years of pre-clinical research. However, in vitro studies prove that the inhibition of dopamine reuptake as a result of binding to the dopamine reuptake pump leads to elevated levels of extracellular dopamine. Modafinil present in Provigil stimulates glutamatergic circuits during inhibition of GABA.

Provigil Generic is supposed to have less abuse potential in comparison to other stimulants due to the lack of any major euphoric or pleasurable effects. There is a possibility that Provigil medication acts by improving the secretion of dopamine, serotonin, non-adrenalin, orexin and other neurotransmitters that perform several regulating functions in the body.

  • Read all the usage instructions mentioned on the prescription label carefully before taking this medication.
  • In case of any doubts regarding the usage of this medication, ask your pharmacist or physician.
  • In the case of narcolepsy and obstructive sleep apnea, once in a day in the morning or as directed by your physician.
  • In case of shift work disorder, take this medication once in a day, about one hour before beginning your work shift.
  • Provigil medication can be taken with or without food.
  • It is mostly prescribed for about 12 weeks or less.
  • Never take this medicine in smaller or larger amounts or for a long duration than advised by your physician.
  • Do not share Provigil with other individuals, particularly with a person who has a history of drug abuse or addiction.
  • Store this medication at room temperature away from the heat and moisture.
  • Do not use this medication if you have a history of allergy or have experienced a skin rash while consuming Modafinil or Armodafinil.
  • Do not take this medication if you are suffering from health problems such as angina, cirrhosis, hypertension, mental illness, and drug addiction.

Always remember that your physician has prescribed you this medication as he/she has judged that benefit to you is more than the risk. The most commonly observed side effects of this medication are as follows:

  • Headache
  • Nausea
  • Nervousness
  • Dizziness
  • Insomnia

If any of these side effects worsen or continue for a long time, immediately call your healthcare provider. Several people using this medication do not experience serious side effects.

  • Always consult your doctor while using Provigil over the counter, if you are pregnant, planning for pregnancy or are breast-feeding. It is unknown whether this medication will harm a fetus.
  • This medication can make birth control less effective. Thus, consult your physician for appropriate methods of birth control while using this medication.
  • Avoid beverages containing alcohol and marijuana. These can induce more drowsiness.
  • Also, avoid engaging in activities requiring mental alertness as this drug product is likely to induce dizziness.
  • Street drugs such as methamphetamine can interact with Provigil Generic. So avoid taking these medications together.

What is Provigil used for?

It is a wakefulness-promoting agent. It acts by altering the natural chemical substances called neurotransmitters present in the brain. It is mainly prescribed for treating excessive sleepiness associated with sleep apnea, shift work disorder or narcolepsy.

Is Provigil a narcotic?

It contains Modafinil as the active constituent. In the US, it is categorized as a schedule IV controlled substance as it is likely to develop an addiction.

Can Provigil make you smarter?

Provigil medication improves the concentration of certain neurotransmitters in the brain such as non-adrenalin, serotonin, and dopamine. It can improve brain power in people with low performance.

Is this medication safe long term?

Provigil medication is usually well-tolerated at high doses. Numerous large-scale studies have found that there is no possibility of developing a tolerance for this medication. These studies included data of users who had been consuming this medication between nine months to three years.

What are the side effects of this medication?

The most commonly experienced side effects of this medication include headache, nausea, insomnia, nervousness, and dizziness. A very serious side effect to this medication is rare.

Customer Review

Customer Reviews on Provigil

Average Rating: 5 / 5

Donald Gilmore |

Provigil over the counter is a smart drug-containing Modafinil as the active constituent. I had a rotational shift and was suffering from a shift work disorder. I experienced the effect of this medication within an hour after taking it. I ordered this medication at Samrx. This online pharmacy sells medications at discounted rates as compared to its competitors.