Sarcoidosis is a condition where there is abnormal grouping of cells that face inflammation and form nodules in the affected organs
Sarcoidosis can be either chronic or asymptomatic. Generally, the inflammatory cells are seen in the lungs and lymph nodes. But this condition can affect any organ gradually. The symptoms can recur or be absent for many years. Sometimes this disease is too fatal and can lead to failure of the lungs and the respiratory system on them whole.
The cause of this is not totally unknown. It is said that this can be due to hazardous occupations and environmental factors and also reduction of response from the immune system.
As sarcoidosis can take over any organ, symptoms are also very common like some general diseases. Lack of energy and incessant fatigue exists, even if the patient has got enough sleep. Eyes get dry and the knees swell, pain and aches are rampant. Some people also suffer from arthritis due to this.
Skin lesions and dry cough are present. Vision can blur and unnecessary weight loss along with short breaths is among the symptoms. This disease is often confused with cancer due to the formation of the nodule. The less probable ones where the condition is minor may get just rashes.
This may aggravate due to portal hypertension and other liver and heart diseases.
Different organs that can suffer from sarcoidosis
Patients can identify sarcoidosis through x-ray. This appears to be abnormal. The inflammation occurs in the small vessels of blood, smaller bronchi and alveoli. It also causes the fibrosis in the lung parenchyma. Dry rales are revealed in physical examination.
Myocardial sarcoidosis can happen due to acute heart attack. Ventricular arrhythmia can also exist. The vessels of heart can suffer from an asymptomatic condition of this kind.
There is normally biochemical evidence and hepatomegaly involvement of the liver in sarcoidosis. There is an increase in the level of bilirubin, alkaline phosphatase and aminotransferases. Many patients show a sign of these symptoms.
Sarcoidosis can lead to uveoparotitis and uveitis. This may cause blindness and problem in visibility due to retinal inflammation. Uveoparotid fever is due to the paralysis of the cranial nerve and anterior parotitis and uveitis. Scleral nodule can develop into this disease.
Generally, sarcoidosis is not chronic in the skin. The inflammation may disappear in a few weeks. Plaques, subcutaneous nodules, maculopapular eruptions and erythema nodules and lupus pernio may occur in the disease.
Intrathoracic nodes get large in most of the victims. Lymphadenopathy can aggravate due to sarcoidosis. Paratracheal and hilar nodes are involved in this. Manifestation is present in the neck and the head region. There is no pain even if the patient palpitates.
Chances of anemia heighten in people suffering from sarcoidosis. Less circulation of lymphocytes can cause leucopenia. Mostly redistributing of T blood cells helps in reducing these issues. Monocytosis and more or hepatitic enzymes are possible in inflammation.
In sarcoidosis, there is enlargement of parotid and even Xerostomia may occur. The gland may become hard and lose its smoothness.